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Tadalafil Tabletsare a drug designed to help men achieve and maintain a firm erection during sexual activity. This drug works by increasing blood flow to the penis, which helps men to achieve and maintain an erection during sexual stimulation. The drug is a combination of two active ingredients, Cialis and Viagra. Tadalafil belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. It is a type of phosphodiesterase type 5 (PDE5) inhibitor, which helps improve blood flow to the penis during sexual stimulation. This drug is used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). It helps men achieve and maintain a firm erection during sexual activity.

How Does Tadalafil Work?

The main mechanism of tadalafil is to increase blood flow to the penis by relaxing the muscles in the walls of the blood vessels. This relaxation allows for increased blood flow, which helps men achieve and maintain an erection during sexual stimulation. Tadalafil works by inhibiting the PDE5 enzyme, which is responsible for the breakdown and breakdown of cyclic guanosine monophosphate (cGMP). cGMP is a molecule that relaxes the smooth muscle cells in the penis, resulting in an erection. When this relaxation occurs, blood flow to the penis is increased, which allows for increased blood flow.

What Is The Dosage for Tadalafil?

The recommended dosage of Tadalafil is one tablet about one to two hours before sexual activity. It is a tablet that is taken once a day. It is not for use over 24 hours. The effects of Tadalafil on men can last up to 36 hours, although this varies by individual.

Tadalafil Dosage

Tadalafil is available in several dosage forms:

  • 20mg
  • 40mg
  • 80mg
  • 100mg
  • 120mg
  • 180mg
  • 270mg

The recommended dose of Tadalafil is one tablet about one to two hours before sexual activity.

Tadalafil Side Effects

Like all medications, Tadalafil can cause side effects. The most common side effects include:

  • Flushing
  • Headache
  • Nasal congestion
  • Dizziness
  • Blurred vision

Other side effects of Tadalafil may include:

  • Chest pain
  • Drowsiness
  • Stuffy nose
  • Runny nose

If you experience any of these symptoms while taking Tadalafil, it is important to talk to your doctor right away. They may adjust your dosage or recommend other medications. If you have any concerns about side effects or have questions about your treatment, contact your doctor or pharmacist.

Tadalafil Dosage Tips

Tadalafil is available in different strengths, including 20mg, 40mg, and 80mg tablets. Depending on the dosage strength you are prescribed, it may be taken on an empty stomach, with or without food. However, it is important to note that Tadalafil is only available with a doctor’s prescription.

If you are prescribed Tadalafil tablets, you will need to follow a few simple precautions to ensure safe and effective use of the drug. Before taking Tadalafil, your doctor will ask you to keep a diary of your symptoms and perform certain tests to ensure you are taking the medication correctly.

If you have an issue with your erectile dysfunction, you should seek medical advice from your GP or from your doctor. They will assess your most commonly and severity of symptoms and possible underlying health conditions. If you suffer from erectile dysfunction, your GP or doctor may refer you to a specialist sexual health clinic.

You should consult your GP or your doctor before taking this medicine if you have a history of hereditary degenerative retinal disorders.

Common causes of erectile dysfunction

Erectile dysfunction occurs when a man is unable to achieve or maintain an erection sufficient for sexual intercourse. It can be caused by several factors, including physical, psychological, and an environmental causes.

Several conditions can cause erectile dysfunction:

  • Conditions that can increase your risk of developing erectile dysfunction
  • Conditions that can cause or worsen erectile dysfunction
  • Conditions that can damage your retina or cause permanent vision loss

Serious complications of erectile dysfunction

A serious problem that can lead to permanent vision loss is erectile dysfunction, or impotence. This is a rare condition that can affect only men and is usually reversible if symptoms are treated.

Erectile dysfunction can also be caused by conditions that can damage your retina or cause permanent vision loss, such as glaucoma, a hormone-related eye disease, or retinitis pigmentosa.

You should stop taking this medicine and see a doctor if you experience:

  • vision changes
  • loss of vision
  • painful erection

How to use this medicine

This medicine is available only with your doctor’s prescription.

Your doctor or your doctor will decide if this medicine is right for you. With other medicines, there is a chance that they may need to take extra time to work out if you have erectile dysfunction.

Before you take this medicine, read the patient information leaflet that comes with your medicine. You can read it over in more detail on the packaging.

References:

  1. Lamaceutical. GoodRx. (ed).erala.com.uk. (n.d.). Retrieved from to.
  2. Perala P. (ed). ( 1979).Pharmacopeial Specifications in Cardiovascular Drugs: What the Interactions are and What Might Be Newer (Approved Drug Applications).The World Journal of Cardiology, Vol. 100, Issue 2, 1 Feb; 2, 5-6:
  3. (Edinburgh). (1872). (2d ed.). Retrieved from: (1979).. Accessed 2 Dec 2014
  4. Kulkarni P, Kumar K, Pallanthi A, Ramesh A, and Thakkar R (2013). Dapoxetine: clinical use and efficacy, safety and tolerability of dapoxetine versus placebo in the treatment of erectile dysfunction.
All medicines on the World Health Organization’s List of Essential Medicines - Drugs Notved

Please refer to the section “Directions for use” on the website of the Drugs for Human Use (DOH) –

Note:This document is not intended to be a complete guide for all health conditions. Results and warnings may vary, depending on the specific medical advice and treatment being taken, so it’s always a good practice to ask your health care professional for personalized advice. A complete list of conditions can be found in the “Directions for use” section of the website.

  1. National Library of Medicine.. Retrieved from: 2 Dec 2014
  2. National Centre for Biotechnology Information..
  3. National Centre for Health Research..
All drugs on the World Health Organization’s List of Essential Medicines - Drugs Notved

Please refer to the section “Directions for use” on the website of the Drugs for Human Use (DOH) -

What is erectile dysfunction?

Erectile dysfunction (ED) is a common sexual problem that affects millions of men worldwide. It can be caused by various factors, including physical, psychological, and an environmental cause.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
EU access to and education about drug Interactions
Interaction NameDescription
Alpha-blocker/ AntihypertensivesCialis (tadalafil) may enhance the blood pressure-lowering effects of certain medications. While balance is essential, expert prescribing may advise using CYP2C19 inhibitors with CYP2C19 inhibitors.
Alpha-blocker/ CYP2C9 InhibitorsUse with CYP3A4 inhibitors with CYP2C19 inhibitors is common, particularly in individuals with high blood pressure or liver disease.
Cialis can enhance the levels of tadalafil by interfering with its metabolism by blocking this enzyme. This increases the availability of nitric oxide in the body, which lowers blood pressure.
Cialis can worsen side effects like headaches or increase the time to panic attacks in sensitive individuals.

Cialis 5mg

Cialis 5mg is a medication that contains the active ingredient tadalafil, which is a phosphodiesterase type 5 (PDE5) inhibitor. It is used to treat erectile dysfunction, premature ejaculation, and male sexual dysfunction. It works by increasing blood flow to the penis, which helps to achieve and maintain an erection. Cialis 5mg is taken orally, approximately 30 minutes before sexual activity. Cialis is also available in tablet form.

Cialis is typically taken with or without food. However, the recommended dosage and timing of use can vary depending on individual factors and the condition being treated. Cialis 5mg is known for its effectiveness in treating erectile dysfunction. This medication works by increasing blood flow to the penis and helps to achieve and maintain an erection. It does not cause sexual arousal. It is not known if Cialis 5mg is safe for use during pregnancy or breastfeeding.

How to use Cialis 5mg?

Cialis 5mg is typically taken orally, about 30 minutes before sexual activity. It is usually taken once or twice a day. Cialis 5mg should be taken on an empty stomach with a full glass of water. It is recommended to take Cialis on an empty stomach with a full glass of water, as this will help reduce the likelihood of side effects.

Cialis 5mg side effects

Like any medication, Cialis 5mg can cause side effects. Some side effects may be more common in older men. However, most side effects are mild and go away on their own.

Common side effects of Cialis include headache, facial flushing, nasal congestion, indigestion, back pain, muscle aches, and dizziness. If you experience any side effects while taking this medication, seek medical attention immediately. If you experience any severe or persistent side effects, such as a severe allergic reaction, sudden vision loss, or an inability to urinate, consult your doctor.

Tadalafil 20mg

Tadalafil 20mg is an alpha-2 adrenergic inhibitor, which is the same active ingredient as Cialis and is used to treat erectile dysfunction and pulmonary arterial hypertension. It works by increasing blood flow to the penis, helping to achieve and maintain an erection. It is not used by women or children. However, it is not recommended to take this medication in women or children.

Tadalafil 20mg may cause low blood pressure. It does not affect the way other medications work. You should only take tadalafil 20mg if you are sexually active and have been prescribed tadalafil 5mg.

Pregnancy

Pregnancy is a possibility with Cialis 5mg. It is not recommended to use this medication during pregnancy. Cialis 5mg is not recommended to use during breastfeeding.

Breastfeeding

It is not recommended to use Cialis 5mg during breastfeeding. It is not known if this medication passes into breast milk.

Common side effects of Cialis 5mg include headache, facial flushing, nasal congestion, indigestion, back pain, muscle aches, and dizziness.

Dosage

The dosage of Cialis 5mg varies depending on the condition being treated and individual factors. It is typically taken on an empty stomach with a full glass of water, with or without food. The dosage may be adjusted based on how much you need to take.

Missed Dose

If you miss a dose of Cialis 5mg, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.